Biomaterials and autologous cell therapies designed to support tissue repair
Orthocell develops and manufactures regenerative medicine products for use by appropriately qualified healthcare practitioners across surgical and musculoskeletal settings. Our portfolio spans treatments for bone, nerve and tendon, with technologies designed to support the biological processes involved in tissue repair, regeneration and functional recovery. Orthocell’s products include collagen-based medical devices and autologous cell therapies used in the management of peripheral nerve injuries, guided bone and tissue regeneration, chronic tendon pathology and articular cartilage defects.
Advancing tissue repair through cellular science
Orthocell’s origins are strongly linked to autologous cell science: the use of a patient’s own cells to support the repair of damaged tissue.
The company’s cell therapy platforms include technologies for tendon and cartilage repair. These involve harvesting patient tissue, isolating and expanding specialised cells under controlled laboratory conditions, and reintroducing those cells into the site of injury or degeneration.
The associated intellectual property includes methods for cell selection, expansion, scaffold seeding and clinical application in musculoskeletal repair.
The engineering of high-purity collagen scaffolds designed to support tissue integration has shaped a portfolio of technologies for the repair of bones, nerves and tendons.
Orthocell’s experience in cell biology and extracellular matrix science also informed the development of its collagen medical device platform. It first manufactured high-purity collagen membranes to provide a biologically compatible scaffold for cell therapy implantation.
The collagen platform reflects a core principle of regenerative medicine: the repair environment matters. Effective healing depends not only on surgical technique but also on the interaction among cells, the extracellular matrix, the vascular supply, mechanical stability, and the biomaterial placed at the repair site.
In peripheral nerve surgery, the quality of the repair environment is critical. A tensionless, well-aligned coaptation with minimal epineurial suturing is recognised as an important factor in supporting axonal regeneration across the repair site.
Nerve repair devices were introduced to help improve the technical quality of coaptation, reduce suture burden and support nerve alignment.
Orthocell’s collagen-based approach is designed to provide a soft, conformable and biologically compatible interface around the repair site, supporting a protected environment for nerve healing while reducing unnecessary mechanical constraint.
Orthocell’s history in cellular science continues to inform its product development, manufacturing and clinical strategy.